Leeds Fetal Medicine Unit Website

Two vessel umbilical cord (as a result of a single umbilical artery)

Definition	Single umbilical cord artery (rather than normal double)
Incidence	6:1000 live births
Diagnosis	Ultrasound appearances of cord or bladder (usually vessel either side)
Gestation at diagnosis	12 weeks onwards
Known chromosomal or genetic association	Yes, seen in association with trisomy 18 or 13. NOT trisomy 21.
Further investigations	Karyotype is associated with other risk factors for chromosomal abnormality. If normal consider serial growth scans as 15% associated with IUGR.
Differential Diaganosis	None
Prognosis	Excellent if isolated
Recurrance risk	Low
Research Studies

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