Leeds Fetal Medicine Unit Website

Transposition of the Great Arteries

Definition	Switching of the main vessels leaving the heart
Incidence	0.2/1000 livebirths
Diagnosis	Ultrasound (classical feature outflow tracts parallel as they leave the heart)
Gestation at diagnosis	16-22 weeks
Known chromosomal or genetic association	No
Further investigations	Fetal Echocardiogram
Differential Diaganosis	Double outlet right ventricle Tetralogy of Fallot
Prognosis	Good. Surgery required soon after birth, operative mortality 3-5%
Recurrance risk	1.5%
Research Studies	None

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